In this first volume, which runs up to the 1950s, we meet prehistoric monkeys who spread a peculiar virus; a Native American shaman whose sexual explorations mutate into occult visions; and early English settlers who establish loving same-sex couples only to fall prey to the forces of bigotry. George Washington and Alexander Hamilton revel in unexpected intimacies, and John Wilkes Booth's motives for assassinating Abraham Lincoln are thoroughly revised.